From The Lancet:
The following story should be taken as a serious warning against use of a laptop computer in a literal sense. The patient, a previously healthy 50-year-old scientist and the father of two children, had been writing a report one evening in his home. Sitting comfortable in an armchair, he had placed his laptop computer on his lap while writing for about 1 h. The next day he noticed irritation and oedema of his penile prepuce. Furthermore, the ventral part of his scrotal skin had turned red, and there was a blister with a diameter of about 2 cm. …
Ouch