NHLBI stops estrogen and progestin study – increased cancer risk

Big news:     NHLBI has stopped early a major clinical trial of the risks and benefits of combined estrogen and progestin in healthy menopausal women due to an increased risk of invasive breast cancer. The large multi-center trial, a component of the Women's Health Initiative (WHI), also found increases in coronary heart disease, stroke, and pulmonary embolism in study participants on estrogen plus progestin compared to women taking placebo pills.

Should we take our patients off prempro?  Seems so.  Wyeth's stock took a hit.  Hmm